  
After experiencing heartache, Adrian a.k.a. Ada (Rustom Padilla)- a conservative homosexual, leaves the city with his cousin Aruba (Pauleen Luna). Relocating to a quaint province to start a new life and a parlor business, she meets her assistant Didi (Chokoleit), her new secret love Dodong (Alfred Vargas) and a multitude of Wacky characters including Dodong's brother Poldo (Alwyn Uytingco), the peculiar couple Aling Britney (Minnie Aguilar) and Mang Justin (Christian Vasquez) and her arch-rival when it comes to Dodong's affections Krystal (Joy Viado).
When a mysterious stone engraved with the words "Zaturnnah" falls from the sky one night, Ada gulps it down and he is magically transformed into Zsazsa Zaturnnah (Zsazsa Padilla), a super heroine with immense strength and extraordinary beauty. In the pursuit of liberty, truth, justice and loads of excellent hair coloring, she fearlessly defends her newfound home from a giant frog, zombies running amuck and from the over bearing Amazonistas from Planet X, led by a man-hater Queen Femina (Pops Fernandez).
Based on characters from the out classic graphic novel by writer/art director Carlo Vergara, Zsazsa Zaturnna Ze Moveeh is bound to make audiences laugh, cry, fall in love and ze enjoy every minute of it.
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